Core Facilities

Core Facilities

The Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital is committed to providing scientists with a world-class technology infrastructure. Shared facilities and core laboratories provide investigators with access to tools and technologies they would otherwise have to seek out or develop on their own, usually at great cost.

The 344,000 square foot building includes shared lab support on each floor. Currently, following seven Core laboratories are operational -

   Animal Behavior Core — Provides sophisticated behavioral analyses of rodent models
   Bioinformatics Core— Offers computational expertise for genomic, metabolomic, and proteomic research
   In situ Hybridization Core — Performs non-radioactive RNA in situ hybridization assays on individual tissues and for high-throughput applications 
   In vivo Neurophysiology Core — Performs and offers training in rodent neurophysiological assays
   Microscopy Core — Offers expertise and access to the state-of-the-art fluorescence, confocal, two-photon and multi-photon laser-scanning microscopes and electron microscopes
   Neuroconnectivity Core — Provides access to technologies and reagents to perform neurotropic viral expression, optogenetic manipulation, and in vivo electrophysiological stimulation/recordings
   Neuropathology Core — Performs histological and immunohistochemical assays to faciliate neuropathological analyses of human and mouse tissues