Core Facilities

Core Facilities

The Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital is committed to providing scientists with a world-class technology infrastructure. Shared facilities and core laboratories provide investigators with access to tools and technologies they would otherwise have to seek out or develop on their own, usually at great cost.

The 344,000 square foot building includes shared lab support on each floor. At this time, 8core laboratories are in place:

  • Behavioral core — sophisticated behavioral analyses of animal models
  • Bioinformatics — computational expertise for genomic, metabolomic, and proteomic research
  • Microscopy core — state-of-the-art fluorescence microscopy, electron microscopy, including two photon and multiphoton laser-scanning microscopy
  • Mouse ES/Transgenic core — knock-in/knock-out and transgenic services
  • Neuropathology core — intensive neuropathological analyses of human and mouse tissues
  • RNA In situ hybridization core — including robotics, tissue culture, and imaging
  • Synaptic Physiology core — in vitro neurophysiological/EEG monitoring
  • In vivo Neurophysiology core — continuous in vivo rodent behavioral and neurophysiological/EEG monitoring